Abstract
SEVERAL experimental systems have been developed to test the cytotoxic effect of sensitized lymphocytes on target cells in vitro1–7. In a previous report8 we presented evidence for the inhibitory effect of lymphocytes on DNA synthesis in the target cells. Although this effect is strongest for the sensitized lymphocytes, the fact that it is also shown by the non-sensitized lymphoid cells casts some doubt as to its specificity. A further examination of this phenomenon was therefore undertaken.
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MING, SC., KLEIN, E. & KLEIN, G. Inhibition of DNA Synthesis of Target Cells in vitro by Sensitized Lymphocytes. Nature 215, 1390–1392 (1967). https://doi.org/10.1038/2151390a0
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DOI: https://doi.org/10.1038/2151390a0
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