Abstract
LEPTOSPIRAL agglutinins or agglutinating factors have been reported in poikilothermic vertebrates collected from the natural environment1–5. Pathogenic leptospires have been isolated from6,7 and experimentally propagated1,8 in lower vertebrates. During follow-up of a human leptospirosis outbreak associated with swimming9,10, leptospires (unidentified) were isolated from the kidney tissue of frogs collected at the place of swimming11. Frogs were inoculated with the leptospiral isolate in an attempt to: (a) produce infection and disease; (b) measure an antibody response; (c) propagate the organism; and (d) develop carriers and shedders.
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References
Van Thiel, P. H., Antonie van Leeuwenhoek, 14, 129 (1948).
Combiesco, D., Sturdza, N., Radu, I., Sefer, M., and Nicolesco, I., Arch. Roumaines Path. Exp. Microbiol., 18, 361 (1959). (Abstr. in Bull. Hyg., 35, 1006; 1960.)
Van der Hoeden, J., Syenberg, J. E., and Evenchik, Z., Nature, 190, 95 (1961).
White, F. H., Amer. J. Vet. Res., 24, 179 (1963).
Andrews, R. D., Reilly, J. R., Ferris, D. H., and Hansen, L. E., Bull. Wildlife Dis. Assoc., 1, 55 (1965).
Ferris, D. H., Rhoades, H. E., Hansen, L. E., Galton, M., and Mansfield, M. E., Cornell Vet., 51, 405 (1961).
Plesko, I., Janovicova, E., and Lac, J., Zbl. Bakt. I., 192, 482 (1984). (Abstr. in Vet. Bull., 34, 580; 1964.)
Abudulla, P. K., and Karstad, L., Zoonoses Res., 1, 295 (1962).
McCulloch, W. F., Diesch, S. L., Braun, J. L., Top, F. H., and Nelsen, C. E., Eleventh Pacific Science Congress, Tokyo, Japan (1966).
Diesch, S. L., and McCulloch, W. F., Public Health Rep., 81, 299 (1966).
Diesch, S. L., McCulloch, W. F., Braun, J. L., and Ellinghausen, jun., H. C., Nature, 209, 939 (1966).
Ellinghausen, jun., H. C., and McCullough, W. C., Amer. J. Vet. Res., 26, 39 (1965).
Galton, M. M., Menges, R. W., Shotts, jun., E. B., Nahmias, A. J., and Heath, C. W., Public Health Service Publication No. 951, 1962 (U.S. Department of Health, Education and Welfare).
Ellinghausen, jun., H. C., and McCullough, W. G., Amer. J. Vet. Res., 26, 45 (1965).
Johnson, R. C., and Rogers, P., J. Bact., 87, 422 (1964).
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DIESCH, S., MCCULLOCH, W. & BRAUN, J. Experimental Leptospirosis in Frogs. Nature 214, 1139–1140 (1967). https://doi.org/10.1038/2141139a0
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DOI: https://doi.org/10.1038/2141139a0
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