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Senescence and the Fidelity of Protein Synthesis in Drosophila

Abstract

The possibility that ageing may be a consequence of the failure of cells to maintain accurate protein synthesis has prompted experiments in which the larvae of Drosophila melanogaster are treated with agents expected to induce errors in protein synthesis. Treatment of larvae with amino-acid analogues or with streptomycin does indeed decrease the life-span of adults.

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HARRISON, B., HOLLIDAY, R. Senescence and the Fidelity of Protein Synthesis in Drosophila. Nature 213, 990–992 (1967). https://doi.org/10.1038/213990a0

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