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Membrane Active Drugs and the Aggregation of Human Blood Platelets

Nature volume 213, pages 3538 (07 January 1967) | Download Citation

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Abstract

The aggregation of human blood platelets is stimulated by ADP and other materials, and is known to take place in two stages. Studies with chlorpromazine, imipramine and related compounds indicate that they affect the second stage

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References

  1. 1.

    , and , The Physiology of Blood Platelets (Grune and Stratton, London, 1965).

  2. 2.

    , Nature, 202, 765 (1964).

  3. 3.

    , and , Thromb. Diath. Haemorrh., 7, 480 (1962). , Acta Physiol. Scand., 56, suppl. 195 (1962).

  4. 4.

    , Thromb. Diath. Haemorrh., 9, 264 (1963).

  5. 5.

    , in Symposium on Physiology of Haemostasis and Thrombosis (Detroit 1966) (edit. by Johnson, S. A., and Seegers, W.) (Charles C. Thomas, Springfield, in the press).

  6. 6.

    , Nature, 211, 140 (1966).

  7. 7.

    , J. Clin. Path., 14, 140 (1961).

  8. 8.

    , and , Brit. J. Haemat., 10, 78 (1964).

  9. 9.

    , , , and , J. Pharm. Pharmacol., 18, 616 (1966).

  10. 10.

    , Nature, 194, 927 (1962).

  11. 11.

    , and , Biochem. J. (in the press).

  12. 12.

    , Nature, 200, 763 (1963).

  13. 13.

    , J. Clin. Path., 17, 275 (1964).

  14. 14.

    , Thromb. Diath. Haemorrh., 9, 248 (1963).

  15. 15.

    , , and , in Ciba Foundation Symposium on Cellular Injury (edit. by de Reuck, A. V. S., and Knight, J.), 187 (Churchill, London, 1964).

  16. 16.

    , in Ciba Foundation Symposium on Enzymes and Drug Action (edit. by Mongar, J. L., and de Beuck, A. V. S.), 344 (Churchill, London, 1962).

  17. 17.

    , and , Biochem. Pharmacol., 12, 47 (1963).

  18. 18.

    , , , and , Ann. N.Y. Acad. Sci., 107, 1139 (1963).

  19. 19.

    , , and , Nature, 194, 297 (1962). , and , Acta Pharm. Tox., 22, 293 (1965). , Acta Physiol. Scand., 64, suppl. 248 (1965).

  20. 20.

    , , , and , Brit. J. Pharmacol., 15, 35 (1960).

  21. 21.

    , , and , Intern. J. Neuropharmacol., 3, 623 (1964).

  22. 22.

    , , and , Nature, 185, 99 (1960).

  23. 23.

    , and , Nature, 212, 1544 (1966).

  24. 24.

    , Thromb. Diath. Haemorrh., 8, 455 (1962).

  25. 28.

    , Ann. Roy. Coll. Surg., 36, 200 (1965).

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Affiliations

  1. M.R.C. Thrombosis Research Group, Department of Pharmacology, Royal College of Surgeons, Lincoln's Inn Fields, London, W.C.2

    • D. C. B. MILLS
    •  & G. C. K. ROBERTS

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https://doi.org/10.1038/213035a0

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