Abstract
IN experiments on the uptake of iron-59 by mouse erythrocytes the isotope is usually administered intravenously (jugular or tail vein), or intraperitoneally. Anaesthesia and incision are required for jugular venipuncture, and part of the iron-59 may be lost by extravasation. Damage to the abdominal organs or accidental injection of iron-59 into the intestine can occur during intraperitoneal injection. The subcutaneous injection of iron-59 is more rapid and is free from the problems that may be encountered during intravenous or intraperitoneal administration.
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THOMSON, R. Incorporation of Subcutaneously Administered Iron-59 by Mouse Erythrocytes. Nature 212, 925 (1966). https://doi.org/10.1038/212925a0
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DOI: https://doi.org/10.1038/212925a0
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