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Genetic and Physiological Variations of Esterases in Mouse Serum

Abstract

INTRASPECIES variation and multiple forms of serum esterases and cholinesterases have been reported in human and animal sera1–3. Some of these enzymes, with different electrophoretic patterns, have been shown to be genetically controlled by autosomal allelic genes. The various levels of activity of the pig serum arylesterase4 and the human serum cholinesterase6 have been demonstrated to be genetically determined by multiple allelic genes. The activity levels of certain esterases in mouse epididymis6 and kidney7 are, however, dependent on male sex hormone. The differences among breeds or individuals in catalytic activities of esterases and multiple forms of cholinesterase in equine plasma have been reported previously8. In this connexion, the present communication deals with the inheritance of activity levels of serum esterase and the effect of pregnancy on activity levels of multiple forms of serum cholinesterase in mice.

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References

  1. Popp, R. A., and Popp, D. M., J. Heredity, 53, 111 (1962).

    Article  CAS  Google Scholar 

  2. Harris, H., Hopkinson, D. A., and Robson, E. B., Nature, 196, 1296 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Oki, Y., Oliver, W. T., and Funnell, H. S., Nature, 203, 605 (1964).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Augustinsson, K.-B., and Olsson, B., Nature, 187, 924 (1960).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Liddell, J., Nature, 193, 561 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. Allen, J. M., and Hunter, R. L., J. Histochem. Cytochem., 8, 50 (1960).

    Article  CAS  PubMed  Google Scholar 

  7. Shaw, C. R., and Koen, A. L., Science, 140, 70 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Oki, Y., Oliver, W. T., and Funnell, H. S., Canad. J. Physiol. Pharmacol., 43, 147 (1965).

    Article  CAS  Google Scholar 

  9. Smithies, O., Biochem. J., 71, 585 (1959).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Poulik, M. D., J. Immunol., 82, 502 (1959).

    CAS  PubMed  Google Scholar 

Download references

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OKI, Y., TAKEDA, M. & NISHIDA, S. Genetic and Physiological Variations of Esterases in Mouse Serum. Nature 212, 1390–1391 (1966). https://doi.org/10.1038/2121390a0

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  • DOI: https://doi.org/10.1038/2121390a0

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