Abstract
INFECTIOUS drug resistance that can be transferred in vitro from a donor bacterium to a sensitive recipient bacterium can also be transferred in vivo. Transfer has been shown to occur in mice which have had their normal intestinal flora reduced by the preliminary feeding of antibiotics. In such mice the donor and recipient strains become well established and multiply in the intestine1,2.
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References
Kasuya, M., J. Bacteriol., 88, 322 (1964).
Guinée, P. A. M., Antonie v. Leeuwenhoek, 31, 314 (1965).
Smith, H. W., and Halls, S., Brit. Med. J., i, 266 (1966).
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WALTON, J. In vivo Transfer of Infectious Drug Resistance. Nature 211, 312–313 (1966). https://doi.org/10.1038/211312a0
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DOI: https://doi.org/10.1038/211312a0
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