Abstract
The microdot is a means of concealing messages (steganography)1 that was developed by Professor Zapp and used by German spies in the Second World War to transmit secret information2. A microdot (“the enemy's masterpiece of espionage”2) was a greatly reduced photograph of a typewritten page that was pasted over a full stop in an innocuous letter2. We have taken the microdot a step further and developed a DNA-based, doubly steganographic technique for sending secret messages. A DNA-encoded message is first camouflaged within the enormous complexity of human genomic DNA and then further concealed by confining this sample to a microdot.
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References
- 1.
Kahn, D. The Codebreakers (Scribner, New York, 1996).
- 2.
Hoover, J. E. Reader's Digest 48, 1–6 (April 1946).
- 3.
Clayton, P. T. et al. Arch. Dis. Child 79, 109–115 (1998).
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Author notes
- Viviana Risca
Present address: Paul D. Schreiber High School, Port Washington, New York 11050, USA
Affiliations
Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029, USA e-mail: cbancro@smtplink.mssm.edu
- Catherine Taylor Clelland
- & Carter Bancroft
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