Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Strain Differences in Mouse Mammary Tissue Sensitivity to Prolactin and Somatotrophin in Organ Culture

Abstract

THE lactogenic activities of ovine prolactin and bovine somatotrophin have been investigated in several strains of inbred mice, and a spectrum of responses was reported1,2. Prolactin was lactogenic in all strains, with some variations in sensitivity encountered. On the other hand, whereas somatotrophin showed considerable activity on tissues from some strains, other strains were much less reactive, and a single strain was completely unresponsive to the lactogenic effects of this hormone.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Nandi, S., and Bern, H. A., J. Nat. Cancer Inst., 24, 907 (1960).

    CAS  PubMed  Google Scholar 

  2. Bern, H. A., and Nandi, S., Prog. Exp. Tumor Res., 2, 90 (1961).

    Article  CAS  Google Scholar 

  3. Nandi, S., Proc. Soc. Exp. Biol. and Med., 108, 1 (1961).

    Article  CAS  Google Scholar 

  4. Rivera, E. M., Endocrinol., 74, 853 (1964).

    Article  CAS  Google Scholar 

  5. Elias, J. J., and Rivera, E. M., Cancer Research, 19, 505 (1959).

    CAS  PubMed  Google Scholar 

  6. Rivera, E. M., and Folley, S. J. (unpublished work).

  7. Barnawell, E. B., thesis, Univ. of Calif., Berkeley (1964); Amer. Zool., 4, abst., 117 (1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

RIVERA, E. Strain Differences in Mouse Mammary Tissue Sensitivity to Prolactin and Somatotrophin in Organ Culture. Nature 209, 1151–1152 (1966). https://doi.org/10.1038/2091151a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2091151a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing