Abstract
IN a recent study1 it was found that in mice of certain strains inoculated with Graffi virus, removal of thymus had practically no effect in modifying the incidence of leukaemia while it favoured to a considerable extent the shift of neoplastic transformation from lymphoid to myeloid tissues. In addition, it was noted that in intact mice with generalized myeloid leukaemia the thymus appeared free from disease, or in some cases showed leukaemic changes of the lymphatic type. It was then considered of interest to study more systematically the morphology of thymic tissue in animals which developed myeloid leukaemia following inoculation of Graffi virus at birth.
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References
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Stansly, P. G., and Soule, H. D., J. Nat. Cancer Inst., 29, 1083 (1962).
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CHIECO-BIANCHI, L., FIORE-DONATI, L., TRIDENTE, G. et al. Lymphatic Neoplastic Transformation of Thymus in Mice with Myeloid Virus-induced Leukaemia. Nature 208, 697–698 (1965). https://doi.org/10.1038/208697a0
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DOI: https://doi.org/10.1038/208697a0
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