Abstract
PARTIAL immunity against a virulent and lethal strain of T. cruzi has been obtained in mice by several procedures1–4. All these procedures lead to a limited protection and are characterized by the appearance of parasites in the blood. The use of killed flagellates induces little or no resistance against the virulent strain1,5, suggesting that a mild host infection is an indispensable prerequisite for the development of even partial immunity.
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FERNANDES, J., HALSMAN, M. & CASTELLANI, O. Effect of Actinomycin D on the Infectivity of Trypanosoma cruzi. Nature 207, 1004–1005 (1965). https://doi.org/10.1038/2071004a0
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DOI: https://doi.org/10.1038/2071004a0
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