Abstract
ALTHOUGH it has rarely been used for this purpose the microelectrophoretic technique1 is well suited for the detection of antibody adsorbed to bacterial cells. The antigen–antibody reactions between a single strain of Streptococcus pyogenes type 6 matt variant (N.C.T.C. 8302) and antisera for its type-specific M and T antigens, and for the group specific C antigen, have been investigated in this way. The type-specific sera were fully absorbed to remove heterologous cross-reactions. The group-specific sera were unabsorbed but showed no cross-reactions with other groups.
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References
Gittens, G. J., and James, A. M., Anal. Biochem., 1, 478 (1960).
Hill, M. J., James, A. M., and Maxted, W. R., Biochim. Biophys. Acta, 66, 264 (1963).
Hill, M. J., James, A. M., and Maxted, W. R., Biochim, Biophys. Acta, 75, 402 (1963).
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HILL, M., JAMES, A. & MAXTED, W. Application of Particle Electrophoresis to the Detection of Antibody bound to Cells of Streptococcus pyogenes. Nature 202, 187–188 (1964). https://doi.org/10.1038/202187a0
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DOI: https://doi.org/10.1038/202187a0
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