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Systemic Antifungal Activity of Isobutyl O-Coumarate in Apple

Abstract

O-COUMARIC acid, a structural analogue of caffeic acid which forms part of the chlorogenic acid molecule, has been shown to inhibit the growth and sporulation of Venturia inaequalis, the causal fungus of apple scab. Sporulation was inhibited in culture and the incidence of disease was reduced, when inoculated shoot tips of the variety Cox's Orange Pippin were injected with an aqueous M/100 solution of sodium O-coumarate1. Spray applications of the acid have been ineffective, however, probably owing to lack of leaf penetration caused by the highly polar nature of the molecule.

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References

  1. Kirkham, D. S., and Flood, A. E., J. Gen. Microbiol., 32, 123 (1963).

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  2. Kirby, A. H. M., and Hunter, L. D. (in preparation).

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KIRKHAM, D., HUNTER, L. Systemic Antifungal Activity of Isobutyl O-Coumarate in Apple. Nature 201, 638–639 (1964). https://doi.org/10.1038/201638b0

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