Abstract
PROLONGED administration of copper to rats results in an increase of liver copper content1–4, indicating that the liver is not able to eliminate the administered copper completely. The mechanism of this retention of copper is not known, and it seemed of interest to investigate the effect of copper loading on the handling of tracer doses of copper-64 by the liver.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Herkel, W., Beitr. Path. Anat., 85, 513 (1930).
Boyden, R., Potter, V. R., and Elvehjem, C. A., J. Nutr., 15, 397 (1938).
Howell, J. S., J. Path. Bact., 77, 473 (1959).
Barka, T., Scheuer, P. J., Schaffner, F., and Popper, H. (to be published).
Osborn, S. B., Roberts, C. N., and Walshe, J. M., Clin. Sci., 24, 13 (1963).
Gitlin, D., Hughes, W. L., and Janeway, C. A., Nature, 188, 150 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCHEUER, P., BARKA, T. Effect of Copper Loading on Uptake and Excretion of Copper-64 by Rat Liver. Nature 201, 1135–1136 (1964). https://doi.org/10.1038/2011135a0
Issue Date:
DOI: https://doi.org/10.1038/2011135a0
This article is cited by
-
Changes in the binding of copper and zinc in the rat bile during 24 hours after application
Archives of Toxicology (1974)
-
Role of Protein in Removal of Copper from the Liver
Nature (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.