Abstract
Ewald and Hübener1 have recently described a new method for the determination of tyrosine-α-ketoglutarate transaminase activity. In their procedure, the p-hydroxyphenylpyruvate generated in the transamination reaction was converted on standing in alkali to an unknown ‘chromogen’ absorbing maximally at 331 mµ with ɛ334 mµ = 16,200. The Ewald and Hübener technique represents another report of the oxidative cleavage of phenylpyruvates to aromatic aldehydes and oxalate according to equation (1) and depends on the strong absorption of the phenolate ion of P-hydroxybenzaldehyde. 
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PITT, B. Oxidation of Phenylpyruvates to Aromatic Aldehydes and Oxalate. Nature 196, 272–273 (1962). https://doi.org/10.1038/196272a0
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DOI: https://doi.org/10.1038/196272a0
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