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Protection of Primates against Lethal Doses of X-Radiation

Abstract

THE protective effect of 2-amino ethylisothiouronium bromide (AET) against lethal doses of total body X-radiation administered to rats and mice is well documented1,2. In the dog, however, the protective effect of AET is obscured by the toxic response to the drug when levels sufficient to be protective are administered3. AET and cysteine administered simultaneously, however, were effective against a lethal exposure of X-radiation in dogs.

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References

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VANLANCKER, J., WOLF, R. & MOWBRAY, J. Protection of Primates against Lethal Doses of X-Radiation. Nature 194, 492–493 (1962). https://doi.org/10.1038/194492a0

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  • DOI: https://doi.org/10.1038/194492a0

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