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Soluble Collagen in Bone

Nature volume 192, pages 758–759 (1961)Cite this article

Abstract

CONSIDERABLE efforts have been made, so far, to investigate the physico-chemical as well as the biochemical nature of soft tissue collagen such as skin and tendon, especially. In refs. 1–3 it is suggested that the soluble collagen is the precursor of collagen. However, only scanty information has been provided in regard to the important role of bone collagen in the formation of bone4. Trials in refs. 5 and 6 have not been successful in proving the existence of soluble collagen.

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References

  1. Orekhovich, Y. N., Third Intern. Congr. Biochem. Communications, 50 (1955).

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  3. Harkness, R. D., Marko, A. M., Muir, H. M., and Neuberger, A., Biochem. J., 56, 558 (1954).

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  4. Neuman, W. F., and Neuman, M. W., The Chemical Dynamics of Bone Mineral, 169 (1058).

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Authors and Affiliations

  1. Department of Biochemistry, School of Dentistry, Tokyo Medical and Dental University,

    S. ARAYA, S. SAITO & S. NAKANISHI

  2. Department of Serology, Tokyo University,

    Y. KAWANISHI

Authors
  1. S. ARAYA
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  2. S. SAITO
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  3. S. NAKANISHI
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  4. Y. KAWANISHI
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ARAYA, S., SAITO, S., NAKANISHI, S. et al. Soluble Collagen in Bone. Nature 192, 758–759 (1961). https://doi.org/10.1038/192758a0

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