Abstract
A STRAIN of Claviceps paspali Stevens and Hall has previously been shown to be capable of producing lysergic acid α-hydroxyethylamide in submerged fermentation1,2. Examination of chromatograms (solvent n-butanol/acetic acid/water, 4 : 1 : 5) of culture fluids at the end of the fermentation period revealed the presence of a mobile (RF 0.83) spot showing bright blue fluorescence, not giving the Ehrlich–Van Urk reaction for lysergic acid derivatives but giving a blue-violet colour with ferric chloride.
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References
Arcamone, F., Bonino, C., Chain, E. B., Ferretti, A., Pennella, P., Tonolo, A., and Vero, Lidia, Nature, 187, 238 (1960).
Arcamone, F., Chain, E. B., Ferretti, A., Minghetti, A., Pennella, P., Tonolo, A., and Vero, Lidia, Proc. Roy. Soc. (in the press).
Terni, G., Enatsu, T., and Tokaku, H., J. Fermentation Tech. (Japan), 31, 65 (1953).
Brady, H. G., Thorpe, W. V., and White, K., Biochem. J., 46, 271 (1950).
King, F. E., Gilks, J. H., and Partridge, M. W., J. Chem. Soc., 4206 (1955).
Goris, A., and Canal, H., Bull. Soc. Chim. France, 3, 1982 (1936).
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ARCAMONE, F., CHAIN, E., FERRETTI, A. et al. Formation of 2,3-Dihydroxybenzoic Acid in Fermentation Liquors during the Submerged Culture Production of Lysergic Acid α-Hydroxyethylamide by Claviceps paspali Stevens and Hall. Nature 192, 552–553 (1961). https://doi.org/10.1038/192552a0
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DOI: https://doi.org/10.1038/192552a0
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