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Site of Binding of Chromium-51 to Hæmoglobin

Nature volume 189, pages 1019–1020 (1961)Cite this article

Abstract

Gray and Sterling1 have shown that when red blood cells are incubated with sodium chromate labelled with chromium-51, the latter enters the red cell and becomes firmly attached to intra-erythrocytic hæmoglobin. This tagging became the basis for in vivo studies of red cell volume and estimations of red cell life-span2,3. Despite its wide application in clinical medicine, little is known of the actual hæmoglobin-chromium-51 binding mechanism or site.

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Authors and Affiliations

  1. Radioisotope Department, U.S. Naval Hospital, National Naval Medical Center, Bethesda, Maryland

    HOWARD A. PEARSON & KENNETH M. VERTREES

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  1. HOWARD A. PEARSON
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  2. KENNETH M. VERTREES
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PEARSON, H., VERTREES, K. Site of Binding of Chromium-51 to Hæmoglobin. Nature 189, 1019–1020 (1961). https://doi.org/10.1038/1891019a0

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