Abstract
SHIMIZU et al. have reported several interesting histochemical results of the locus cœruleus of the mammalian brain—the strong activity of acid phosphatase1 and cholinesterase2 but rather poor action of respiratory enzymes3,4, and further, characteristically strong monoamine oxidase activity5. The last finding led us to suppose that some aromatic monoamines such as catechol amines and serotonin would be concentrated in the locus. Although Falck and Hillarp6 recently reported that no chromaffin reaction could be observed in the hypothalamus and the caudate nucleus, and concluded that noradrenalin and dopamine are not stored in a small number of nerve cells of these regions, they did not examine the locus cœruleus. In the present investigation several histochemical reactions including argentaffin, Schmorl's, chromaffin, azo-coupling and Gibbs's reaction were carried out in mammalian brain tissues containing the locus cœruleus.
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MAEDA, T., ABE, T. & SHIMIZU, N. Histochemical Demonstration of Aromatic Monoamine in the Locus Cœruleus of the Mammalian Brain. Nature 188, 326–327 (1960). https://doi.org/10.1038/188326b0
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DOI: https://doi.org/10.1038/188326b0
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