Abstract
As part of a study of skin sensitization to benzyl-pencillin, I have investigated, the behaviour of D-benzylpenicilloic acid (4-carboxy-5,5′-dimethyl-α-phenylacetamido-2-thiazolidine acetic acid). This compound was found to give allergic cross-reactions of the contact dermatitis type with both benzylpenicillin and D-penicillamine (unpublished work).
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References
Tabachnick, M., Eisen, H. N., and Levine, B. B., Nature, 174, 701 (1954).
Cited in : “Chemistry of Penicillin”, 573 edit. by Clarke, G. T., Johnson, J. R., and Robinson, R. (Princeton Univ. Press, Princeton, N.J., 1948).
Levine, B. B., Nature, see preceding communication.
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LEVINE, B. Formation of D-Penicillamine-Cysteine Mixed Disulphide by Reaction of D-Benzylpenicilloic Acid with Cystine. Nature 187, 940–941 (1960). https://doi.org/10.1038/187940a0
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DOI: https://doi.org/10.1038/187940a0
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