Abstract
THIS work was undertaken in an attempt to determine whether a difference could be demonstrated in the platelet counts of the blood of the rabbit right and left heart ventricles. That such a difference might occur suggested itself from the recent work of Sharnoff and Kim1,2, which studies revealed that megakaryocytes are present normally in the lung blood vessels of all mammals, where they appear to break up in the pulmonary capillary anastomoses into platelets. Therefore, it was postulated that if the lung vessels were a possible site of platelet formation, the blood of the left heart ventricle could contain a higher number of platelets than that of the right ventricle. The difference in number of platelets, it was believed, would depend only on the number of megakaryocytes present and breaking up at any one time in the lung vessels.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Sharnoff, J. G., and Kim, E. S., Amer. Med. Assoc. Arch. Path., 66, 176 (1958).
Sharnoff, J. G., and Kim, E. S., Amer. Med. Assoc. Arch. Path., 66, 340 (1958).
Howell, W. H., and Donahue, D. D., J. Exp. Med., 65, 177 (1937).
Bierman, H. R., Amer. J. Surg., 89, 130 (1955).
Sharnoff, J. G., Nature, 184, 75 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SHARNOFF, J., SCARDINO, V. Platelet-Count Differences in Blood of the Rabbit Right and Left Heart Ventricles. Nature 187, 334–335 (1960). https://doi.org/10.1038/187334a0
Issue Date:
DOI: https://doi.org/10.1038/187334a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.