Abstract
MANY chemical substances have been investigated for their ability to protect animals against the lethal effects of total-body radiation1. Of these, S-β-aminoethylisothiouronium bromide hydrobromide is one of the most effective if administered before exposure. It produces a remarkable degree of protection to total-body radiation in mice2. Similar protection is afforded to the monkey if given 150–250 mgm./kgm. prior to administration of 650 r. whole-body X-radiation3. The following experiments were carried out to test whether S-β-aminoethylisothiouronium bromide was capable of protecting tissues against local irradiation.
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WALTER, J., SLOME, D. Effect of S-β-aminoethylisothiouronium Bromide Hydrobromide on X-ray Damage to Guinea Pig Skin. Nature 186, 177 (1960). https://doi.org/10.1038/186177a0
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DOI: https://doi.org/10.1038/186177a0
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