Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Maintenance of Parathyroid Tissue Fragments on Agar Substrates

Nature volume 184, pages 1734–1735 (1959)Cite this article

Abstract

EXPLANTATION of organ fragments on to plasma clots1 or soft agar2 contained in Maximow slides or embryological watch glasses permits the preservation and development of organotypic tissue in vitro. The recent finding that mammalian cell strains can be cultivated for extended periods with minimal effort on nutrient media solidified with agar3,4 suggested the use of agar substrates to simplify and improve maintenance of functional organ fragments prior to surgical transplanatation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Strangeways and Fell, Proc. Roy. Soc., B, 99, 340 (1925–1926).

    Article  ADS  Google Scholar 

  2. Wolff and Heffen, Texas Repts. Biol. Med., 10, 463 (1952).

    CAS  Google Scholar 

  3. Wallace and Hanks, Science, 128, 658 (1958).

    Article  ADS  CAS  Google Scholar 

  4. Keefe, Merchant and Sticker, Bacteriol. Proc. (1959).

  5. Escamilla, Kempe, Crane, Goldman, and Gordon, Ann. Int. Med., 46, 649 (1957).

    Article  CAS  Google Scholar 

  6. Hanks and Wallace, Proc. Soc. Exp. Biol. and Med., 98, 188 (1958).

    Article  CAS  Google Scholar 

  7. Castleman, Armed Forces Inst. of Path., Washington, Sec. IV, Fas. 15, F15 (1952).

  8. Bernstein and Moore, J. Clin. Endocrin. and Metab., 19, 224 (1959).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Leonard Wood Memorial, Department of Bacteriology and Immunology, and Surgical Research Laboratory, Harvard Medical School, Boston, Mass.

    JOHN H. WALLACE, GEORGE J. HILL, JEAN M. McCARTHY & JOHN R. BROOKS

Authors
  1. JOHN H. WALLACE
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. GEORGE J. HILL
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. JEAN M. McCARTHY
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. JOHN R. BROOKS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

WALLACE, J., HILL, G., McCARTHY, J. et al. Maintenance of Parathyroid Tissue Fragments on Agar Substrates. Nature 184, 1734–1735 (1959). https://doi.org/10.1038/1841734a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1841734a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing