Abstract
IT has been shown that hæm containing iron-59 can be crystallized from the reticulocytes of blood samples to which iron-59 has been added prior to incubation at 37°C.; but the mature mammalian erythrocyte does not synthesize hæm in this way1,2. The results of an investigation of the nature and kinetics of this phenomenon in reticulocytes and avian cells suggests that there are at least two phases; first the entry of iron into the cell and secondly the synthesis of hæm from this iron.
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CLARK, P., WALSH, R. Synthesis of Hæm by Circulating Blood Cells. Nature 184, 1730–1731 (1959). https://doi.org/10.1038/1841730b0
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DOI: https://doi.org/10.1038/1841730b0
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