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Antibody Status of Mice and Response of their Litters to Parotid Tumour Virus (Polyoma Virus)

Abstract

IN earlier work there was observed a tendency for pleomorphic tumours of the parotid gland to appear only in certain litters of C3H mice that had received inoculations of preparations from leukæmia tissues1. This ‘litter effect’ was also observed in tests with a more active preparation of tumour-inducing material propagated in a continuously passaged tissue culture line of a murine leukæmia, P-388D 1 2.

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References

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LAW, L., DAWE, C., ROWE, W. et al. Antibody Status of Mice and Response of their Litters to Parotid Tumour Virus (Polyoma Virus). Nature 184, 1420–1421 (1959). https://doi.org/10.1038/1841420a0

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