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Rise of Serum Folic Acid - Levels after Injection of Vitamin B12 in Nutritional Macrocytic Anæmia

Abstract

ALTHOUGH certain similarities between folic acid and vitamin B12 as agents involved in hæmopoiesis, nucleic acid synthesis and single-carbon transfers are well known, there is very little information on the manner in which these two chemically dissimilar vitamins affect each other. We wish to make a preliminary report of observations which show that the administration of vitamin B12 causes a rise in the serum folic acid - level in patients with nutritional macrocytic anæmia.

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NARAYANAN, M., SHENOY, K. & RAMASARMA, G. Rise of Serum Folic Acid - Levels after Injection of Vitamin B12 in Nutritional Macrocytic Anæmia. Nature 178, 1347–1348 (1956). https://doi.org/10.1038/1781347a0

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