Abstract
IN two separate experiments it has been found that, 24 hr. after the administration of bovine pituitary growth hormone to mice with the hereditary syndrome of obesity and hyperglycæmia (1 mgm. of growth hormone per mouse), changes had occurred in the amounts of insulin and hyperglycæmic-glycogenolytic factor extractable from the pancreas using a standardized acid alcohol technique1. In each experiment values for insulin and hyperglycæmic-glycogenolytic factor values were compared in the following four groups of animals (ten or twelve animals per group) : obese-hyperglycæmic mice and their non-obese sibs treated with growth hormone, and two groups of the same description but not treated with growth hormone.
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CLARKE, D., WRENSHALL, G. & MAYER, J. Effects of Pituitary Growth Hormone on the Insulin and Hyperglycæmic-glycogenolytic Factor extractable from the Pancreas of Obese-Hyperglycæmic Mice. Nature 177, 1235 (1956). https://doi.org/10.1038/1771235a0
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DOI: https://doi.org/10.1038/1771235a0
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