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Hydrophilic Penicillins produced by Penicillium chrysogenum

Abstract

IT has been shown1–3 that a species of Cephalosporium produces an antibacterial substance, cephalosporin N, which is a new type of penicillin characterized by its insolubility in most organic solvents and by a similar order of activity against Gram-positive and Gram-negative bacteria4.

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References

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  2. Crawford, K., Heatley, N. G., Boyd, P. F., Hale, C. W., Kelly, B. K., Miller, G. A., and Smith, N., J. Gen. Microbiol., 6, 47 (1952).

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  3. Abraham, E. P., Newton, G. G. F., Crawford, K., Burton, H. S., and Hale, C. W., Nature, 171, 343 (1953).

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  4. Heatley, N. G., and Florey, H. W., Brit. J. Pharm. and Chemotheropy, 8, 252 (1953).

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HALE, C., MILLER, G. & KELLY, B. Hydrophilic Penicillins produced by Penicillium chrysogenum . Nature 172, 545–546 (1953). https://doi.org/10.1038/172545b0

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