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Strongyloidiasis after unrelated nonmyeloablative allogeneic stem cell transplantation

Bone Marrow Transplantation volume 38, pages 393–394 (2006)Cite this article

A 54-year-old male presented with complex partial seizures, mild eosinophilia (10%) and a normal WBC count in April 2000. Over the next 2 years his clinical history was notable for the development of Klebsiella pneumonia × 2, 16 episodes of acute bronchitis and persistent eosinophilia.

In January 2003, a bone marrow biopsy showed increased eosinophils (10%), magnetic resonance imaging (MRI) of the brain was normal, and multiple stool samples were negative for ova and parasites, including Strongyloides stercoralis. A diagnosis of idiopathic hypereosinophilic syndrome (IHES) was made, based on classic criteria1 defined as: absolute eosinophil count >1500 for >6 months, no underlying cause for eosinophilia, and signs and symptoms of organ involvement (seizures, bronchitis and pneumonia). No therapy was offered at that point. The diagnosis was confirmed at UT-MDACC in October 2003. The patient had always resided in the Gulf coast area at the Texas–Louisiana border. There was no significant travel history within or outside the US.

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Authors and Affiliations

  1. Department of Blood and Marrow Transplantation, UT-MD Anderson Cancer Center, Houston, TX, USA

    M H Qazilbash, N T Ueno, C Hosing, M De Lima, A Massaro, Z Rivera & R E Champlin

  2. Department of Leukemia, UT-MD Anderson Cancer Center, Houston, TX, USA

    J Cortes

  3. Department of Pathology, UT-MD Anderson Cancer Center, Houston, TX, USA

    M Deavers

  4. Department of Infectious Diseases, Infection Control and Employee Health, UT-MD Anderson Cancer Center, Houston, TX, USA

    J A Adachi

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  1. M H Qazilbash
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  2. N T Ueno
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  3. C Hosing
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  4. M De Lima
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  6. A Massaro
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  7. Z Rivera
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  8. M Deavers
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  9. J A Adachi
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  10. R E Champlin
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Correspondence to M H Qazilbash.

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Qazilbash, M., Ueno, N., Hosing, C. et al. Strongyloidiasis after unrelated nonmyeloablative allogeneic stem cell transplantation. Bone Marrow Transplant 38, 393–394 (2006). https://doi.org/10.1038/sj.bmt.1705448

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