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Autologous blood pleurodesis for pneumothorax complicating graft-versus-host disease-related bronchiolitis obliterans

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Bronchiolitis obliterans (BO) is a manifestation of chronic graft-versus-host disease (GVHD) after allogeneic haemopoietic stem cell transplantation. Complications associated with this include persistent air-leak syndromes such as pneumothorax. Many methods have been described for treating this condition, both surgical and nonsurgical. We describe an 8-year-old boy with acute lymphoblastic leukaemia complicated by chronic GVHD-related BO, and subsequent pneumothorax with persistent air leak, who was treated successfully with autologous blood pleurodesis.

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Correspondence to A J Vora.

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Chadwick, C., Marven, S. & Vora, A. Autologous blood pleurodesis for pneumothorax complicating graft-versus-host disease-related bronchiolitis obliterans. Bone Marrow Transplant 33, 451–453 (2004). https://doi.org/10.1038/sj.bmt.1704370

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