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Successful treatment of severe hemorrhagic cystitis after hemopoietic cell transplantation by selective embolization of the vesical arteries

Bone Marrow Transplantation volume 31, pages 923–925 (2003)Cite this article

Summary:

Hemorrhagic cystitis (HC) is a common and sometimes life-threatening complication of hemopoietic cell transplantation (HCT) occurring in 7–52% of transplant recipients. In this setting it is usually either related to the use of cyclophosphamide or to a viral infection (BK, JC viruses and adenovirus type 11). Treatment is based on hyperhydration, platelet and blood-cell transfusions, bladder irrigation and pain management. Where these measures have failed to control HC, numerous therapeutic approaches including surgery have been tried with poor success. We report two HCT patients with severe HC successfully treated with selective embolization of the vesical arteries.

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Acknowledgements

This work was supported in part by Grants SGR 2000 121 from Generalitat de Catalunya and FIJC-01/P-CR and FIJC-02/P-EM from José Carreras International Fundation, Barcelona, Spain.

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Authors and Affiliations

  1. Hematology Department, BMT Unit, Institute of Hematology and Oncology, Postgraduate School of Hematology, Spain

    E Giné, M Rovira, E Carreras & E Montserrat

  2. Unit of Interventional Vascular Radiology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain

    I Real, M Burrel & J Montaña

Authors
  1. E Giné
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  2. M Rovira
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  3. I Real
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  4. M Burrel
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  5. J Montaña
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  6. E Carreras
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  7. E Montserrat
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Correspondence to M Rovira.

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Giné, E., Rovira, M., Real, I. et al. Successful treatment of severe hemorrhagic cystitis after hemopoietic cell transplantation by selective embolization of the vesical arteries. Bone Marrow Transplant 31, 923–925 (2003). https://doi.org/10.1038/sj.bmt.1703954

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  • DOI: https://doi.org/10.1038/sj.bmt.1703954

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