Summary:
Methicillin-resistant Staphylococcus aureus (MRSA) is a common infectious pathogen during stem cell trans-plantation. We report a case of meningoencephalitis with multiple abscess formation caused by MRSA, which occurred in a 4-year-old boy soon after allogeneic peri-pheral blood stem cell transplantation. We successfully cured the infection with a combination of intravenous and intrathecal vancomycin.
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Acknowledgements
The authors thank Michihiro Shino and Yoshiko Kawamoto, Department of Pharmacy, for analyzing the pharmacokinetics of VCM. This research was supported by a Grant-in-Aid for Scientific Research from the Ministry of Health, Labor and Welfare.
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Matsubara, H., Makimoto, A., Higa, T. et al. Successful treatment of meningoencephalitis caused by methicillin-resistant Staphylococcus aureus with intrathecal vancomycin in an allogeneic peripheral blood stem cell transplant recipient. Bone Marrow Transplant 31, 65–67 (2003). https://doi.org/10.1038/sj.bmt.1703799
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DOI: https://doi.org/10.1038/sj.bmt.1703799
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