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Fatal graft-versus-host disease following HLA-mismatched donor lymphocyte infusion

Bone Marrow Transplantation volume 28, pages 623–625 (2001)Cite this article

Abstract

We report the case of a 10-year-old boy with molecular relapse of CML following unrelated donor BMT who developed fatal grade 4 acute GVHD of the gut and liver following one antigen-mismatched donor lymphocyte infusion. Previous experience of donor lymphocyte infusion in the HLA-mismatched setting is reviewed and the role of adoptive immunotherapy in this situation is discussed. Bone Marrow Transplantation (2001) 28, 623–625.

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Authors and Affiliations

  1. Departments of Bone Marrow Transplantation and Pathology, Great Ormond Street Hospital for Sick Children, London, UK

    PJ Amrolia, K Rao, O Slater, A Ramsay, PA Veys & DKH Webb

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  1. PJ Amrolia
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  2. K Rao
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  3. O Slater
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  4. A Ramsay
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  5. PA Veys
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  6. DKH Webb
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Amrolia, P., Rao, K., Slater, O. et al. Fatal graft-versus-host disease following HLA-mismatched donor lymphocyte infusion. Bone Marrow Transplant 28, 623–625 (2001). https://doi.org/10.1038/sj.bmt.1703195

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