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Graft-Versus-Host Disease

Pancreatic insufficiency in patients with chronic graft-versus-host disease

Bone Marrow Transplantation volume 27, pages 163–166 (2001)Cite this article

Abstract

Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition. Bone Marrow Transplantation (2001) 27, 163–166.

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Authors and Affiliations

  1. Department of Oncology, Hematologic Malignancies, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    G Akpek, JL Valladares, J Margolis & GB Vogelsang

  2. Department of Medicine, Gastroenterology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    L Lee

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  1. G Akpek
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  2. JL Valladares
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  3. L Lee
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  4. J Margolis
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  5. GB Vogelsang
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Akpek, G., Valladares, J., Lee, L. et al. Pancreatic insufficiency in patients with chronic graft-versus-host disease. Bone Marrow Transplant 27, 163–166 (2001). https://doi.org/10.1038/sj.bmt.1702769

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