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Allogeneic bone marrow transplantation-related transmission of human T lymphotropic virus type I (HTLV-I)

Bone Marrow Transplantation volume 26, pages 1235–1237 (2000)Cite this article

Abstract

We report here the first case report of bone marrow transplantation (BMT)-related transmission of human T lymphotropic virus type-I (HTLV-I). Antibodies against HTLV-I-associated antigens (anti-HTLV-I) were detected in the serum from the BMT recipient 12 days post BMT. IgG against gag core proteins (anti-p19 and anti-p24) appeared earlier than IgM against gag and env proteins (anti-p19, anti-p24 and anti-gp46) during seroconversion. The data presented here differs from blood transfusion-related seroconversion. This phenomenon may be due to the engraftment of anti-HTLV-I producing cells from the donor. Bone Marrow Transplantation (2000) 26, 1235–1237.

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Authors and Affiliations

  1. Second Department of Internal Medicine, Oita Medical University, Hasama-Oita, Japan

    H Kikuchi, E Ohtsuka, K Ono, T Nakayama, Y Saburi, K Tezono, M Ogata, M Iwahashi & M Nasu

  2. Blood Transfusion Center, Oita Medical University, Hasama-Oita, Japan

    H Kikuchi

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  1. H Kikuchi
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  2. E Ohtsuka
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  3. K Ono
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  4. T Nakayama
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  5. Y Saburi
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  6. K Tezono
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  7. M Ogata
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  8. M Iwahashi
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  9. M Nasu
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Kikuchi, H., Ohtsuka, E., Ono, K. et al. Allogeneic bone marrow transplantation-related transmission of human T lymphotropic virus type I (HTLV-I). Bone Marrow Transplant 26, 1235–1237 (2000). https://doi.org/10.1038/sj.bmt.1702698

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  • DOI: https://doi.org/10.1038/sj.bmt.1702698

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