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Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation

Abstract

There is growing evidence for a graft-versus-myeloma effect following allogeneic stem cell transplantation. We add to this evidence by reporting complete remission achieved by withdrawal of immunosuppression in a patient with multiple myeloma progressing after HLA-identical sibling peripheral stem cell transplantation. De novo chronic graft-versus-host disease coincided with the anti-myeloma effect and responded to treatment. The patient remains in complete remission 3 years after transplant.

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Libura, J., Hoffmann, T., Passweg, J. et al. Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation. Bone Marrow Transplant 24, 925–927 (1999). https://doi.org/10.1038/sj.bmt.1701980

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  • DOI: https://doi.org/10.1038/sj.bmt.1701980

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