Abstract
A 44-year-old man with splenectomised refractory autoimmune thrombocytopenic purpura (AITP) of 10 years’ duration underwent an autologous, T cell-depleted marrow transplant following conditioning with thiotepa and CY. There was no response to the transplant procedure. This is the fourth case in the literature to show failure following autologous stem cell transplantation, although complete, steroid-independent remissions were obtained in the first two patients for over 1 year.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Marmont, A., van Lint, M., Occhini, D. et al. Failure of autologous stem cell transplantation in refractory thrombocytopenic purpura. Bone Marrow Transplant 22, 827–828 (1998). https://doi.org/10.1038/sj.bmt.1701431
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.bmt.1701431
Keywords
This article is cited by
-
Strategien zur Behandlung von Thrombozytopenien im Kindesalter
Monatsschrift Kinderheilkunde (2006)
-
Refractory Evans' syndrome treated with allogeneic SCT followed by DLI. Demonstration of a graft-versus-autoimmunity effect
Bone Marrow Transplantation (2003)
-
Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: Getting closer to a cure?
International Journal of Hematology (2002)
-
Allogeneic stem cell transplantation for Evans syndrome
Bone Marrow Transplantation (2001)
-
Stem cell transplantation for treatment of severe autoimmune diseases: current status and future perspectives
Bone Marrow Transplantation (2000)