Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Report
  • Published:

Autoreactive antibodies following autologous peripheral blood stem cell transplantation

Bone Marrow Transplantation volume 22, pages 729–731 (1998)Cite this article

Abstract

A 35-year-old woman diagnosed with multiple myeloma (IgG, λtype, stage IIIA) received an autologous peripheral blood stem cell transplant (PBSCT). She was euthyroid without autoreactive antibodies prior to the transplant. The patient complained of malaise, weight loss and low grade fever 1 month after transplant, despite rapid haematopoietic recovery. Thyroid function tests on day 34 revealed hyperthyroidism associated with anti-thyroid peroxidase antibody. Antinuclear antibody was also detected, and platelet-associated immunoglobulin was increased. These findings disappeared spontaneously by day 62 without treatment. Autoimmune diseases may occur transiently after autologous PBSCT.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

Author information

Authors and Affiliations

  1. First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan

    F Ishikawa, H Shigematsu, H Gondo, T Okamura & Y Niho

Authors
  1. F Ishikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H Shigematsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H Gondo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T Okamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Y Niho
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ishikawa, F., Shigematsu, H., Gondo, H. et al. Autoreactive antibodies following autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 22, 729–731 (1998). https://doi.org/10.1038/sj.bmt.1701409

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.bmt.1701409

Keywords

This article is cited by

Search

Advanced search

Quick links