Fluoroacetates and Allied Compounds

Abstract

WE have recently recorded1 the synthesis and examination during the War of highly toxic fluorine compounds having powerful miotic action, containing the >POF group and known as fluoro-phosphonates. In the present communication a brief accounts given of extensive work on the synthesis and examination of toxic fluorine compounds of an entirely different type carried out at Cambridge during the War by an Extra-Mural Ministry of Supply research team working under our direction. These compounds contain, in general, the —CH2F group, and have usually been spoken of collectively as the ‘fluoroacetates’. For security reasons during the War, this work was not published, though reports (which were also made available to American workers) have from time to time been submitted to the Ministry of Supply.