Abstract
DR. T. K. WITH'S suggestion1 that carotenoids, such as cryptoxanthin and β-carotene, are vitamins in their own right commands considerable sympathy, but we do not think, that the data advanced in that communication settle the point. The efficiency of utilization and the storage of vitamin A in the liver of the rat and the chick are affected by many factors which control the growth response or quantity found. These include the amount and kind of vitamin A fed2, the amount of sparing agents, more particularly the tocopherols fed at the same time3, and the idiosyncrasies of the animal4, which is another way of saying that we do not yet know the complete physiology of vitamin utilization and liver storage.
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With, T. K., Nature, 157, 627 (1946).
Gray, E. L., Hickman, K. C. D., and Brown, E. F., J. Nutrition, 19, 39 (1940).
Hickman, K. C. D., Kaley, M. W., and Harris, P. L., J. Biol. Chem., 152, 321 (1944).
Hickman K. C. D., Jensen, J. L., and Harris, P. L., unpublished data.
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HICKMAN, K. Vitamin Storage and Utilization in the Organism. Nature 158, 269 (1946). https://doi.org/10.1038/158269b0
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DOI: https://doi.org/10.1038/158269b0
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