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Effect of Desoxycorticosterone and its Esters

Nature volume 142, pages 435–436 (1938)Cite this article

Abstract

WORK carried out in our laboratories1 has shown that the output of activity of the male and female sex hormones can be varied almost as desired by suitable esterification. By subcutaneous injection of an oily solution, it can reach quite considerable values ; in particular, the effect of a few days' duration with the free hormone can be raised to several months by using the corresponding esters.

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References

  1. Miescher, K., Wettstein, A., and Tschopp, E., Biochem. J., 30, 1970, 1977 (1936); Miescher, K., Fischer, W. H., and Tschopp, E., NATURE, 140, 726 (1937); Miescher, K., Kägi, H., Scholz, C., Wettstein, A., and Tschopp, E., Biochem. Z., 294, 39 (1937); Miescher, K., Scholz, C., and Tschopp, E., Biochem. J., 32, 141, 725 (1938).

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Authors and Affiliations

  1. Ciba Research Laboratories, Basle

    K. MIESCHER, W. H. FISCHER & E. TSCHOPP

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  1. K. MIESCHER
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  2. W. H. FISCHER
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  3. E. TSCHOPP
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MIESCHER, K., FISCHER, W. & TSCHOPP, E. Effect of Desoxycorticosterone and its Esters. Nature 142, 435–436 (1938). https://doi.org/10.1038/142435b0

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