Abstract
APPLYING a method1 for determining the blood ammonia by which forty determinations may be easily carried out in a few hours on 1 ml. samples, certain curious facts have been discovered. As is well known, ammonia forms in shed and sterile blood, and it has been shown to begin from zero concentration1. In a further study here, it has been observed that the formation goes in a succession of well-marked stages. Five such have been observed over the 24 hours. Such phasic formation has been observed for the rabbit, man and bird, appearing in the blood from each individual but at somewhat varying times, so that averaging the results from many animals will smooth out the curve of formation.
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Conway, E. J., Biochem. J., 29, 2755 (1935).
György, P., and Rothler, R., Biochem. Z., 187, 194 (1927).
Schmidt, G., Z. physiol. Chem., 179, 243 (1928).
Schmidt, G., Z. physiol. Chem., 208, 185 (1932).
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CONWAY, E., COOKE, R. Ammonia Formation in Shed Blood and a Characteristic Deaminase of the Blood Stream. Nature 139, 627 (1937). https://doi.org/10.1038/139627a0
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DOI: https://doi.org/10.1038/139627a0
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