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Pathologic aspects of AIDS malignancies

Abstract

Since the emergence of the HIV pandemic, a close association between HIV infection and the development of a selected group of cancers has been acknowledged. The introduction of highly active antiretroviral therapy, however, has had a dramatic impact on the incidences of several AIDS-defining malignancies. This suggests the possibility of a direct and indirect role of HIV in HIV-related tumor genesis. The aim of this paper is to review the pathology of AIDS-related malignancies, taking into account the pathogenetic mechanisms and their potential for improving the treatment of these tumors.

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We acknowledge the help of Emma Thorley in editing the manuscript.

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Correspondence to L Leoncini.

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Bellan, C., Falco, G., Lazzi, S. et al. Pathologic aspects of AIDS malignancies. Oncogene 22, 6639–6645 (2003). https://doi.org/10.1038/sj.onc.1206815

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