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Glucometabolic state of in-hospital patients with primary hypertension in sub-population of partial regions in China

Journal of Human Hypertension volume 22, pages 346–351 (2008)Cite this article

Abstract

Abnormal glucose metabolism (AGM) is common but underestimated in patients with coronary heart disease (CHD). Here, we reported 898 in-hospital patients with primary hypertension (PH) at the university hospitals in developed regions of China. Oral glucose tolerance test (OGTT) was performed in those without known type-2 diabetes mellitus (2-DM). A total of 158 patients had known 2-DM and 32 were newly diagnosed as 2-DM by fasting blood glucose (FBG). OGTT revealed that 83 had 2-DM and 296 had impaired glucose tolerance (IGT). The proportion of 2-DM and AGM increased from 21.2 to 30.4% and from 57.5 to 68.7% upon OGTT. Prevalence of AGM and 2-DM increased with the increase of age, and incidence of AGM and 2-DM was significant higher in patients with risk factors (including CHD, overweight, hyperlipidaemia, proteinuria) than those without risk factors mentioned above. Glucose was not sufficiently controlled in 55.1% of the patients with 2-DM upon treatment, well controlled in 35.4% and not controlled in 9.5%. So AGM is also prevalent in PH patients especially the elders and those with risk factors, which was underestimated in most cases. Moreover, much lower awareness, treatment and control of 2-DM occurred in some regions of China, thus strengthening health education for patients and heightening consciousness of doctor are very important and eminent. Except for FBG, more attention should be paid to postprandial blood glucose ignored before, and OGTT should be a routine procedure in PH patients, especially in older patients and those with the factors mentioned above.

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Acknowledgements

We are indebted to our nurses, in particular Ms QiaoHui Xie for her help to us and all the dedicated assistance to patients. We thank professor ErWei Song from Sun Yat-sen Memorial Hospital for editing the paper. We also thank our colleagues, in particular, Dr YingSheng Xue, Dr Chang Fang, Dr NianSang Luo and Dr ZhiBin Huang.

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Author notes

  1. Y-X Chen and X-Q Wang: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Cardiology, The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

    Y-X Chen, J-F Wang, R-Q Nie, S-X Zhou & Y-L Wei

  2. Department of Cardiology, Taizhou Hospital, Wenzhou Medical College, Linhai, ZheJiang

    X-Q Wang, C-F Fang & L-J Tang

  3. Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China

    X-Q Wang

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Correspondence to J-F Wang.

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Chen, YX., Wang, XQ., Wang, JF. et al. Glucometabolic state of in-hospital patients with primary hypertension in sub-population of partial regions in China. J Hum Hypertens 22, 346–351 (2008). https://doi.org/10.1038/sj.jhh.1002327

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  • DOI: https://doi.org/10.1038/sj.jhh.1002327

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