Abstract
The objective of the study was to assess factors associated with treatment satisfaction among patients receiving antihypertensive therapy. A weighted cross-sectional online survey was conducted with hypertensive patients participating in a chronic disease panel in the US. Patients on monotherapy with medications from the following classes were identified: ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), beta blockers (BBs), calcium channel blockers (CCBs), and diuretics. The control group included patients without treatment. Pairwise comparisons between groups were conducted for factors that may affect patients' satisfaction. The study population had a mean age of 54.7±14.2 years and was 56.7% female. Participants with blood pressure (BP) controlled to JNC 7 guidelines were more satisfied with their medication than those with uncontrolled BP (90.3 vs 71.5%, P<0.05). Patients who had not experienced adverse events had higher satisfaction than patients experiencing adverse events (90.9 vs 75.8%, P<0.05). The most frequently self-reported adverse events were frequent urination, sexual dysfunction, and fatigue ranging from 7.0 to 9.6% across classes. The adverse event rates differed by class and were lowest among the ARBs. Patients on ARBs were the most likely to have switched from a previous antihypertensive class as compared to other classes (57.1% ARBs vs 49.8% ACEIs, 38.7% diuretics, 36.3% CCBs, and 31.7% BBs). Physician recommendation was the most common reason for switching. In conclusion, the ability to effectively treat hypertension depends upon a patient's satisfaction with antihypertensive therapy, which may be improved by achieving BP control and minimizing the occurrence of adverse events.
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References
Chobanian AV et al, The National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 Report. JAMA 2003; 289: 2560–2572.
American Heart Association. Heart Disease and Stroke Statistics — 2005 Update. American Heart Association: Dallas, Texas, 2005.
Singer GM, Izhar M, Black HR . Goal-oriented hypertension management translating clinical trials to practice. Hypertension 2002; 40: 464–469.
Hajjar I, Kotchen TA . Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988–2000. JAMA 2003; 290: 199–206.
National Committee for Quality Assurance (NCQA). The State of Health Care Quality. Washington, DC: NCQA, 2004.
Zyzansk SJ, Hulka BS, Cassel JC . Scale for the measurement of ‘satisfaction’ with medical care: modifications in content, format and scoring. Med Care 1974; 12 (7): 611–620.
Ware JE, Davies-Avery A, Stewart AL . The measurement and meaning of patient satisfaction. Health Med Care Services Rev 1978; 1 (1): 1–15.
Hudak PL, Wright JG . The characteristics of patient satisfaction measures. Spine 2000; 25 (24): 3167–3177.
Ross CK, Steward CA, Snacore JM . A comparative study of seven measures of patient satisfaction. Med Care 1995; 33 (4): 392–406.
Ware JE, Hays R . Methods for measuring patient satisfaction with specific medical encounters. Med Care 1998; 26 (4): 393–403.
Carlberg A, Tibblin G . Patient satisfaction in primary health care. A comparative study of two modes of treatment for hypertension. Family Pract 1992; 9: 304–310.
Rajpurkar A, Dhabuwala CB . Comparison of satisfaction rates and erectile function in patients treated with sildenafil, intracavernous prostaglandin E1 and penile implant surgery for erectile dysfunction in urology practice. J Urol 2003; 170: 159–163.
Campbell JL, Kieber GM, Partridge MR . Development of the satisfaction with inhaled asthma treatment questionnaire. Eur Resp J 2003; 22: 127–134.
Zastowny TR, Roghmann KJ, Hengst A . Satisfaction with medical care: replications and theoretic reevaluation. Medical Care 1983; 21 (3): 294–322.
Johnson K, Parker JP, McCombs JS, Cody M . The Kaiser Permanente/USC Patient Consultation Study: patient satisfaction with pharmaceutical services. Am J Health Syst Pharm 1998; 55 (24): 2621–2629.
Schommer JC, Kucukarslan SN . Measuring patient satisfaction with pharmaceutical services. Am J Health Syst Pharm 1997; 54 (23): 2721–2732.
Yancy WS, Macpherson DS, Hanusa BH, Kapoor WN . Patient satisfaction in resident and attending ambulatory care clinics. J Gen Intern Med 2001; 16: 755–762.
Deyo RA, Diehl AK . Patient satisfaction with medical care for low-back pain. Spine 1996; 11 (1): 28–30.
Brown SL, Govier FE . Cadaveric versus autologous fascia lata for the pubovaginal sling: surgical outcome and patient satisfaction. J Urol 2000; 164: 1633–1637.
Slosar PJ et al. Patient satisfaction after circumferential lumbar fusion. Spine 2000; 25 (6): 722–726.
National Center for Health Statistics. web page: http://www.cdc.gov/nchs/about/major/nhanes/nhanes99-02.htm.
Ware JE, Kosinski M, Turner-Bowker DM, Gandek B . How to Score Version 2 of the SF-12 Health Survey, QualityMetric Incorporated, Lincoln, Boston, Massachusetts: Rhode Island and Health Assessment Lab, October 2002.
Physician desk reference online. http://www.pdr.net.
Benson J, Britten N . Patients' decisions about whether or not to take antihypertensive drugs: qualitative study. BMJ 2002; 325: 873–877.
Harewood GC, Wiersema MJ, de Groen PC . Utility of web-based assessment of patient satisfaction with endoscopy. Am J Gastroenterol 2003; 98 (5): 1016–1021.
Sinkowitz-Cochran RL et al. The internet: a practical example of the use of new technology in the assessment of vancomycin use in pediatrics. Am J Infect Control 2001; 28 (6): 459–464.
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This study was supported by a grant from Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.
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Chen, K., Chiou, CF., Plauschinat, C. et al. Patient satisfaction with antihypertensive therapy. J Hum Hypertens 19, 793–799 (2005). https://doi.org/10.1038/sj.jhh.1001899
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DOI: https://doi.org/10.1038/sj.jhh.1001899
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