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  • 9th International Congress on Obesity - Abstracts and Short Reports
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9th International Congress On Obesity - Abstracts and Short Reports

Polyphenolics and fat absorption

International Journal of Obesity volume 28, pages 324–326 (2004)Cite this article

Abstract

OBJECTIVES: To elucidate whether the acute consumption of red wine polyphenolic compounds regulates lipid and lipoprotein metabolism in dyslipidemic postmenopausal women.

DESIGN: Eight dyslipidemic postmenopausal women each consumed a mixed meal accompanied by either water, dealcoholized red wine or alcoholic red wine on three separate visits, in a random order, 2 weeks apart. One fasting and six hourly postmeal blood samples were taken and analyzed for plasma apolipoprotein B48 (apoB48; specific marker of chylomicrons (CM) and their remnants (CMR)); total-, LDL- and HDL-cholesterol; triglycerides (TAG); insulin and glucose at each time point.

RESULTS: There was a decrease in postprandial apoB48 levels after alcoholic and nonalcoholic red wine consumption compared to water.

CONCLUSION: Red wine attenuates postprandial CM and CMR levels in plasma, possibly by delaying the absorption of dietary fat, as suggested by a decrease in plasma apoB48 levels. The reduction of postprandial lipoproteins in circulation after red wine consumption may partly explain the low cardiovascular mortality rates among the French.

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Authors and Affiliations

  1. Department of Nutrition, Dietetics and Food Sciences, Curtin University, Perth Western Australia, Australia

    S Pal, M Naissides & J Mamo

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  1. S Pal
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  2. M Naissides
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  3. J Mamo
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Correspondence to S Pal.

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Pal, S., Naissides, M. & Mamo, J. Polyphenolics and fat absorption. Int J Obes 28, 324–326 (2004). https://doi.org/10.1038/sj.ijo.0802577

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