The top ten charts the articles that have been downloaded most often, in HTML format, from the Acta Pharmacologica Sinica website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.
Top of pageOctober 2009
Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs
Jan O Gordeladze, Farida Djouad, Jean-Marc Brondello, Daniele Noël, Isabelle Duroux-Richard, Florence Apparailly and Christian Jorgensen
doi:10.1038/aps.2009.143
Abstract | Full Text | PDF
The expression of efflux and uptake transporters are regulated by statins in Caco-2 and HepG2 cells
Alice Cristina Rodrigues, Rui Curi, Fabiana Dalla Vecchia Genvigir, Mario Hiroyuki Hirata and Rosario Dominguez Crespo Hirata
doi:10.1038/aps.2009.85
Abstract | Full Text | PDF
SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-
B pathways in RAW 264.7 macrophages
Jun-xia Wang, Li-fei Hou, Yang Yang, Wei Tang, Ying Li and Jian-ping Zuo
doi:10.1038/aps.2009.138
Abstract | Full Text | PDF
Central cholinergic regulation of respiration: nicotinic receptors
Xuesi M Shao and Jack L Feldman
doi:10.1038/aps.2009.88
Abstract | Full Text | PDF
Modulation of KATP currents in rat ventricular myocytes by hypoxia and a redox reaction
Xi-sheng Yan, Ji-hua Ma and Pei-hua Zhang
doi:10.1038/aps.2009.134
Abstract | Full Text | PDF
The natural product Aristolactam AIIIa as a new ligand targeting the polo-box domain of polo-like kinase 1 potently inhibits cancer cell proliferation
Li Li, Xu Wang, Jing Chen, Hong Ding, Yu Zhang, Tian-cen Hu, Li-hong Hu, Hua-liang Jiang and Xu Shen
doi:10.1038/aps.2009.141
Abstract | Full Text | PDF
Atorvastatin attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling
Xiao-mei Bao, Chun-fang Wu and Guo-ping Lu
doi:10.1038/aps.2009.135
Abstract | Full Text | PDF
Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases
Xiao-xia Dong, Yan Wang and Zheng-hong Qin
doi:10.1038/aps.2009.24
Abstract | Full Text | PDF
Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin
Zuo-quan Xie, Gai Liang, Lu Zhang, Qi Wang, Yi Qu, Yang Gao, Li-bo Lin, Sai Ye, Ji Zhang, Hui Wang, Guo-ping Zhao and Qing-hua Zhang
doi:10.1038/aps.2009.126
Abstract | Full Text | PDF
Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts FREE
Yuan James Rao and Lei Xi
doi:10.1038/aps.2008.1
Abstract | Full Text | PDF
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