Acta Pharmacologica Sinica - Figure 1 for article: Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes

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Hydrogen peroxide mobilizes Ca²⁺ through two distinct mechanisms in rat hepatocytes

Hirohiko Sato, Teruko Takeo, Qiang Liu, Kyoko Nakano, Tomohiro Osanai, Sechiko Suga, Makoto Wakui and Jie Wu

Figure 1.

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H₂O₂ elevates [Ca²⁺]_i across two kinetic patterns in a concentration-dependent manner. In the presence of 1 mmol/L Ca²⁺ in the extracellular solution, H₂O₂ was applied to recorded hepatocytes at the concentrations of 50 mol/L (A), 100 mol/L (B), 400 mol/L (C) and 1 mmol/L (D), and the effects on [Ca²⁺]_i were evaluated. The horizontal bar in each trace indicates the exposure period to H₂O₂. Representative traces are typical case from 5-12 experiments tested.

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FIGURE 1

Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes

Figure 1.

Hydrogen peroxide mobilizes Ca²⁺ through two distinct mechanisms in rat hepatocytes