Acta Pharmacologica Sinica

FIGURE 4

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Dehydroepiandrosterone anti-atherogenesis effect is not via its conversion to estrogen

Heng-hui Cheng, Xiao-jing Hu and Qiu-rong Ruan

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Figure 4.

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Immunohistochemical results of VCAM-1 in rabbit artery. (A) group 1, a regular rabbit diet plus 1% cholesterol and 3 % lard (HCD); (B) group 2, 0.25% DHEA was incorporated into the diet of group 1; (C) group 3, the diet of group 1 plus 0.25% DHEA and all-trans retinoic acid (0.6 mgdotkg-1dotd-1); (D) group 4, 0.25% DHEA was incorporated into the regular diet; (E) group 5, a regular diet. Arrow: the brown-yellow particles under the endothelium which indicate VCAM-1 expression. Group 4 and 5 had only basic non-special expression.

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